Anti-UHRF2 antibody produced in rabbit
SIGMA/AV34772 - affinity isolated antibody
Synonym: Anti-Ubiquitin-like, containing PHD and Ring finger domains, 2
Product Type: Chemical
Immunohistochemistry Anti-UHRF2: Cat. No. AV34772: Immunohistochemistry of UHRF2 in Human Heart tissue with UHRF2 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV34772). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 90 kDa |
| NCBI accession no. | NP_690856   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q96PU4 |
| Application: | Rabbit Anti-UHRF2 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml and for IHC (4-8 μg/ml). |
| Biochem/physiol Actions: | UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | UHRF2 is a ubiquitin E3 ligase that also functions as a SUMO E3 ligase for ZNF131. This E3 ligase has been implicated in the cell cycle network. Rabbit Anti-UHRF2 antibody recognizes human, bovine, rat, canine, and mouse UHRF2. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human UHRF2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: TNKLDSVPSTSNSDCVAADEDVIYH |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |