Anti-GABRA3 (AB1) antibody produced in rabbit
SIGMA/AV34981 - IgG fraction of antiserum
Synonym: Anti-γ-Aminobutyric acid (GABA) A receptor, α 3
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 55 kDa |
NCBI accession no. | NP_000799 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | mouse, guinea pig, horse, human, rabbit, dog, rat, bovine |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | P34903 |
Application: | Rabbit Anti-GABRA3 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml. |
Biochem/physiol Actions: | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | GABRA3 codes for the GABAA receptor α3 subunit. Genetic varaiations in GABRA3 have been linked to behavioural despair, bipolar affective disorders and thyrotoxic hypokalaemic periodic paralysis. Rabbit Anti-GABRA3 antibody recognizes bovine, human, mouse, rat, and canine GABRA3. |
Immunogen: | Synthetic peptide directed towards the middle region of human GABRA3 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: AEVVYSWTLGKNKSVEVAQDGSRLN |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |