Anti-CLIC5 antibody produced in rabbit
SIGMA/AV35262 - IgG fraction of antiserum
Synonym: Anti-Chloride intracellular channel 5
Product Type: Chemical
Immunohistochemistry Anti-CLIC5: Cat. No. AV35262: Immunohistochemistry of CLIC5 in Human Intestine tissue with CLIC5 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV35262). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 46 kDa |
| NCBI accession no. | NP_001107558   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rabbit, rat, horse, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9NZA1 |
| Application: | Rabbit Anti-CLIC5 antibody is suitable for immunohistochemistry (4-8 μg/ml) and western blot (1.25 μg/ml) applications. |
| Biochem/physiol Actions: | CLIon Channel5 specifically associates with the cytoskeleton of placenta microvilli. CLIon Channel-5A has a role as a chloride channel in vitro and binds to cortical actin cytoskeleton. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | CLIC5 is a chloride intracellular channel protein involved in hair cell stereocilia formation. It is reportedly stabilizes membrane-actin filament links at the base of stereocilia. It also has a role in the growth and differentiation of C2C12 myoblasts. Rabbit Anti-CLIC5 antibody recognizes human, mouse, rat, pig, zebrafish, chicken, canine, and bovine CLIC5. |
| Immunogen: | Synthetic peptide directed towards the middle region of human CLIC5 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: HPPFLTFNGDVKTDVNKIEEFLEET |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |