Anti-HMGB3 (AB2) antibody produced in rabbit
SIGMA/AV35766 - IgG fraction of antiserum
Synonym: Anti-High-mobility group box 3
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 23 kDa |
NCBI accession no. | NP_005333 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | horse, mouse, human, rat, bovine, guinea pig, dog, rabbit |
storage temp. | −20°C |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | O15347 |
Biochem/physiol Actions: | HMGB3 belongs to high mobility group of proteins and contains HMG box domain that binds DNA. It plays a critical role in DNA replication, nucleosome assembly and transcription. HMGB3 reportedly regulates cell proliferation, migration and invasion of B cells and gastric cancer cells. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human HMGB3 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: NLNDSEKQPYITKAAKLKEKYEKDV |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |