Anti-JAZF1 (AB1) antibody produced in rabbit
SIGMA/AV36246 - affinity isolated antibody
Synonym: Anti-DKFZp761K2222; Anti-JAZF Zinc finger 1; Anti-TIP27; Anti-ZNF802
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV36246). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type Jurkat
Western Blotting Western Blot of JAZF1 in Human HepG2 with JAZF1 antibody at 1 μg/mL
Western Blotting Western Blot of JAZF1 in Human Jurkat with JAZF1 antibody at 1 μg/mL
Western Blotting Western Blot of JAZF1 in Human MCF7 with JAZF1 antibody at 1 μg/mL
Western Blotting Western Blot of JAZF1 in Human NTERA2 with JAZF1 antibody at 1 μg/mL
Western Blotting Western Blot of JAZF1 in Human HeLa with JAZF1 antibody at 1 μg/mL
Western Blotting Western Blot of JAZF1 in Human Adult Placenta with JAZF1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 27 kDa |
| NCBI accession no. | NP_778231   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | guinea pig, mouse, human, rabbit, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q86VZ6 |
| Biochem/physiol Actions: | JAZF1 is a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Juxtaposed with another zinc finger protein 1 (JAZF1) is expressed in the nucleus where it functions as a transcriptional repressor. Alternatively spliced variants of JAZF1 have been identified and associate with various cancers including endometrial stromal tumors. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human JAZF1 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: IDTDPRVLEKQELQQPTYVALSYIN |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |