Anti-NUCB2 (AB2) antibody produced in rabbit
SIGMA/AV36567 - IgG fraction of antiserum
Synonym: Anti-Nucleobindin 2
Product Type: Chemical
Immunohistochemistry Anti-NUCB2 (ab2): Cat. No. AV36567: Immunohistochemistry of NUCB2 in Human Intestine tissue with NUCB2 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV36567). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
Western Blotting Western Blot of NUCB2 in Human COLO205 with NUCB2 antibody at 1 μg/mL
Western Blotting Western Blot of NUCB2 in Mouse Brain with NUCB2 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 46 kDa |
| NCBI accession no. | NP_005004   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | pig, human, dog, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P80303 |
| Biochem/physiol Actions: | NUCB2 is an oncoprotein that is overexpressed in breast cancer. This protein binds calcium and is involved in energy homeostasis and eating regulation in the hypothalamus. It is an important prognostic marker in prostate cancer, promotes osteogenesis and has been identified as anorexigenic and anti-hyperglycemic protein. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human NUCB2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: MMKEHERREYLKTLNEEKRKEEESK |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |