Anti-GJB2 antibody produced in rabbit
SIGMA/AV36608 - IgG fraction of antiserum
Synonym: Anti-Gap junction protein, β 2, 26 kDa
Product Type: Chemical
Immunoblotting Cell Type: fetal lung (Cat. No. AV36608). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type fetal lung
Western Blotting
Western Blot of GJB2 in Lane 1: 4 μg mCx26 elution fraction 6; Lane 2: 4 μg mCx26 elution fraction 7; Lane 3: 4 μg mCx26 elution fraction 6 + other Cx26 antibody; Lane 4: 4 μg mCx26 elution fraction 7 + other Cx26 antibody with GJB2 antibody at 1 μg/mL
Western Blot of GJB2 in Lane 1: 4 μg mCx26 elution fraction 6; Lane 2: 4 μg mCx26 elution fraction 7; Lane 3: 4 μg mCx26 elution fraction 6 + other Cx26 antibody; Lane 4: 4 μg mCx26 elution fraction 7 + other Cx26 antibody with GJB2 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 25 kDa |
| NCBI accession no. | NP_003995   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, horse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P29033 |
| Biochem/physiol Actions: | GJB2 also known as connexin 26 is a gap junction protein that belongs to the connexin family. It is a component of the gap junctions between cells that facilitate the diffusion of low molecular weight materials and ions from cell to cell. Mutations in GJB2 gene is one of the major factors the causes hereditary hearing loss and lethal form of Keratitis-Ichthyosis-Deaf |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human GJB2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: STPALLVAMHVAYRRHEKKRKFIKG |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |