Anti-NR1H3 antibody produced in rabbit
SIGMA/AV38669 - IgG fraction of antiserum
Synonym: Anti-Nuclear receptor subfamily 1, group H, member 3
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 50 kDa |
NCBI accession no. | NP_005684 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | Q13133 |
Biochem/physiol Actions: | NR1H3 belongs to the NR1 subfamily of nuclear receptor superfamily. The NR1 members regulate transcription that is required in lipid homeostasis and inflammation. NR1H3 is also known as LXRα is highly expressed in liver, kidney and intestine. LXRs act as cholesterol sensors and protect the cells from cholesterol overload. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human NR1H3 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: MSLWLGAPVPDIPPDSAVELWKPGA |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |