Anti-MEOX2 (AB3) antibody produced in rabbit
SIGMA/AV38701 - IgG fraction of antiserum
Synonym: Anti-Mesenchyme homeobox 2
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV38701). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 33 kDa |
| NCBI accession no. | NP_005915   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, guinea pig, bovine, horse, human, dog |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P50222 |
| Biochem/physiol Actions: | MEOX2 is a transcription regulator that is essential for limb myogenesis in vertebrates. It regulates the activity of NF-κB and inhibits the activation of vascular endothelial cells in response to hypoxia and proangiogenic factors. MEOX1 and 2 regulate the activity cyclin dependent kinase inhibitors p21(CIP1/WAF1) and p16(INK4a) and induce cell cycle arrest in endothelial cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human MEOX2 |
| Other Notes: | Synthetic peptide located within the following region: REKELVNVKKGTLLPSELSGIGAAT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |