Anti-SMC1A antibody produced in rabbit
SIGMA/AV38780 - affinity isolated antibody
Synonym: Anti-CDLS2; Anti-DKFZp686L19178; Anti-DXS423E; Anti-KIAA0178; Anti-MGC138332; Anti-SB1.8; Anti-SMC1; Anti-Structural maintenance of chromosomes 1A
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 143 kDa |
NCBI accession no. | NP_006297 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, rabbit, guinea pig, mouse, dog, rat, bovine, horse |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | Q14683 |
Biochem/physiol Actions: | Structural maintenance of chromosomes (SMC) proteins maintain the sister chromatid cohesion during the process of cell division. SMC1A is present in the kinetochore, interacts with BRCA1 and ATM proteins indicating a role in DNA repair. It is reportedly involved in the G2/M transition of human glioma cells and G1/S transition of human lung adenocarcinoma cells. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human SMC1A |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: VISLKEEFYTKAESLIGVYPEQGDC |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |