Anti-TRIM16 antibody produced in rabbit
SIGMA/AV38799 - IgG fraction of antiserum
Synonym: Anti-Tripartite motif-containing 16
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 64 kDa |
NCBI accession no. | NP_006461 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | O95361 |
Biochem/physiol Actions: | Tripartite motif containing 16 (TRIM16) is transcriptional repressor belonging to tripartite motif family. It is described as a tumor suppressor protein that interacts with vimentin and E2F1 proteins. It inhibits cell proliferation by inducing cell cycle arrest in G1/S phase in neuroblastoma cells. TRIM16 has the ability to heterodimerize with other TRIM proteins and exhibits E3 ubiquitin ligase activity. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human TRIM16 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: PLPRATAQPPAPLSPDSGSPSPDSG |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |