Anti-STAT1 (AB3) antibody produced in rabbit
SIGMA/AV38933 - affinity isolated antibody
Synonym: Anti-DKFZp686B04100; Anti-ISGF-3; Anti-STAT91; Anti-Signal transducer and activator of transcription 1, 91 kDa
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 87 kDa |
NCBI accession no. | NP_644671 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | horse, human, guinea pig, rat, mouse, rabbit, dog |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | P42224 |
Biochem/physiol Actions: | Signal transducers and activators of transcription (STAT) are a group of proteins that mediate a wide range of cellular functions by activation of gene transcription. STAT1 is activated by IFG-γ, IFN-α, PDGF and IL-6. It acts with important signaling pathways mediated by JAK and MAPK to mediate inflammation and cell viability in response to pathogens and cell stimuli. STAT1 expression levels have prognostic value in in specific types of breast cancer. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human STAT1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: MSQWYELQQLDSKFLEQVHQLYDDS |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |