Anti-METTL3 (AB2) antibody produced in rabbit
SIGMA/AV39390 - IgG fraction of antiserum
Synonym: Anti-
Product Type: Chemical
Immunohistochemistry Anti-METTL3 (ab2): Cat. No. AV39390: Immunohistochemistry of METTL3 in Human Intestine tissue with METTL3 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: fetal thymus (Cat. No. AV39390). Lanes 1. Antibody dilution (concentration) 5.0 μg/mL in cell type fetal thymus
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 64 kDa |
| NCBI accession no. | NP_062826   |
| shipped in | wet ice |
| species reactivity | mouse, rabbit, dog, rat, guinea pig, human, bovine, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q86U44 |
| Application: | Rabbit Anti-METTL3 antibody is suitable for use in western blot (5 μg/ml) and IHC (4-8 μg/ml) applications. |
| Biochem/physiol Actions: | METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransf |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Methyltransferase like 3 (METTL3 or M6A) codes for a 70 kDa subunit of MT-A. This protein forms a heterodimeric complex with METTL14 and subsequently modulates the methylation of the mammalian nuclear RNA, N6-adenosine. Rabbit Anti-METTL3 antibody recognizes bovine, canine, human, mouse, rat, and zebrafish METTL3. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human METTL3 |
| Other Notes: | Synthetic peptide located within the following region: MSDTWSSIQAHKKQLDSLRERLQRR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |