Anti-ANP32A (AB1) antibody produced in rabbit
SIGMA/AV40203 - affinity isolated antibody
Synonym: Anti-Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member A
Product Type: Chemical
Western Blotting JOURNAL CITATION: Species specific differences in use of ANP32 proteins by influenza A virus. By: Long, J. S., Idoko-Akoh, A., et al. in Elife, 2019. PubMed ID: 31159925 Image collected and cropped by CiteAb from the following publication, (https://elifesciences.org/articles/45066), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Immunohistochemistry Anti-ANP32A (ab1): Cat. No. AV40203: Immunohistochemistry of ANP32A in Human Kidney tissue with ANP32A antibody at 4-8 μg/mL.
Immunohistochemistry ANP32A Antibody: Cat. No. AV40203: Immunohistochemistry analysis of ANP32A in Human Heart with ANP32A Antibody Antibody Concentration: 4.0-8.0 μg/mL. Cellular Data: cardiac cell of renal tubule
Immunoblotting Cell Type: Jurkat (Cat. No. AV40203). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 29 kDa |
| NCBI accession no. | NP_006296   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, dog, rat, human, guinea pig, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P39687 |
| Biochem/physiol Actions: | ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ANP32A |
| Other Notes: | Synthetic peptide located within the following region: FNCEVTNLNDYRENVFKLLPQLTYL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |