Anti-KRT18 (AB2) antibody produced in rabbit
SIGMA/AV40206 - IgG fraction of antiserum
Synonym: Anti-Keratin 18
Product Type: Chemical
Immunohistochemistry Anti-KRT18 (ab2): Cat. No. AV40206: Immunohistochemistry of KRT18 in Human Lung tissue with KRT18 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV40206). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
Immunoblotting KRT18 Antibody: Cat. No. AV40206: Western Blot analysis of KRT18 in Human Lung cell lysates with KRT18 Antibody at 1.0 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 47 kDa |
| NCBI accession no. | NP_954657   |
| shipped in | wet ice |
| species reactivity | human, guinea pig, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P05783 |
| Biochem/physiol Actions: | KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human KRT18 |
| Other Notes: | Synthetic peptide located within the following region: ALLNIKVKLEAEIATYRRLLEDGED |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |