Anti-CPSF6 antibody produced in rabbit
SIGMA/AV40697 - IgG fraction of antiserum
Synonym: Anti-Cleavage and polyadenylation specific factor 6, 68 kDa
Product Type: Chemical
Immunohistochemistry Anti-CPSF6: Cat. No. AV40697: Immunohistochemistry of CPSF6 in Human Muscle tissue with CPSF6 antibody at 4-8 μg/mL.
Immunofluorescence Immunofluorescence of CPSF6 in SKOV3 with CPSF6 antibody at 4-8 μg/mL
Immunoblotting Cell Type: Jurkat (Cat. No. AV40697). Lanes 1. Antibody dilution (concentration) 0.3125 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 61 kDa |
| NCBI accession no. | NP_008938   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, bovine, rabbit, human, mouse, guinea pig, dog, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q16630 |
| Biochem/physiol Actions: | CPSF6 is one subunit of a cleavage factor required for 3′ RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3′ end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3′ RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3′ end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human CPSF6 |
| Other Notes: | Synthetic peptide located within the following region: PPLAGPPNRGDRPPPPVLFPGQPFG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |