Anti-PUM2 antibody produced in rabbit
SIGMA/AV40810 - IgG fraction of antiserum
Synonym: Anti-KIAA0235; Anti-PUMH2; Anti-PUML2; Anti-Pumilio homolog 2 (Drosophila)
Product Type: Chemical
Immunoblotting Cell Type: transfected 293T (Cat. No. AV40810). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type transfected 293T
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 117 kDa |
| NCBI accession no. | NP_056132   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, pig, rabbit, dog, human, bovine, mouse, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q8TB72-3 |
| Biochem/physiol Actions: | PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3′-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human PUM2 |
| Other Notes: | Synthetic peptide located within the following region: SSPADKLDSRFRKGNFGTRDAETDG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |