Anti-MATR3 (AB1) antibody produced in rabbit
SIGMA/AV40922 - IgG fraction of antiserum
Synonym: Anti-Matrin 3
Product Type: Chemical
Immunohistochemistry Anti-MATR3 (ab1): Cat. No. AV40922: Immunohistochemistry of MATR3 in Human Muscle tissue with MATR3 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-MATR3 (ab1): Cat. No. AV40922: Immunohistochemistry of MATR3 in Human Muscle tissue with MATR3 antibody at 4-8 μg/mL.
Immunohistochemistry MATR3 Antibody: Cat. No. AV40922: Immunohistochemistry analysis of MATR3 in Human Heart with MATR3 Antibody Antibody Concentration: 4.0-8.0 μg/mL. Cellular Data: Epithelial cells of renal tubule
Immunoblotting Cell Type: Jurkat (Cat. No. AV40922). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 93 kDa |
| NCBI accession no. | NP_061322   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P43243 |
| Application: | Anti-MATR3 (AB1) polyclonal antibody is used to tag matrin 3 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of matrin 3 as a selective nuclear gene transcript stabilizer. |
| Biochem/physiol Actions: | MATR3 is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Matrin 3 (MATR3) is a zinc finger inner nuclear matrix protein with two RNA recognition motifs (RRM). MATR3, which is highly regulated, complexes with and stabilizes specific gene transcripts that are currently being identified. Rev appears to be a MATR3 cofactor. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human MATR3 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: MSKSFQQSSLSRDSQGHGRDLSAAG |
| Specificity: | Anti-MATR3 (AB1) polyclonal antibody reacts with chicken, human, mouse, rat, and bovine matrin 3 proteins. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |