Anti-FN1 antibody produced in rabbit
SIGMA/AV41490 - affinity isolated antibody
Synonym: Fn1 Antibody; Fn1 Antibody - Anti-FN1 antibody produced in rabbit; Anti-CIG; Anti-DKFZp686F10164; Anti-DKFZp686H0342; Anti-DKFZp686I1370; Anti-DKFZp686O13149; Anti-FINC; Anti-FN; Anti-Fibronectin 1
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV41490). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type Jurkat
Western Blotting Western Blot of FN1 in Human Ovary Tumor with FN1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 76 kDa |
| NCBI accession no. | NP_002017   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, dog, sheep, pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P02751 |
| Application: | Anti-FN1 polyclonal antibody is used to tag plasma fibronectin (CIG) for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of fibronectin (CIG) in the adherence of monocytes to cell matricies and solid surfaces coated with materials such as gelatin. |
| Biochem/physiol Actions: | Anti-FN1 polyclonal antibody reacts with human, canine, rabbit, bovine, rat, and mouse plasma fibronectin (CIG). |
| Biochem/physiol Actions: | FN1 is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Fibronectins are a class of immunochemically related glycoproteins present in basement membranes, collective tissues and blood wherein they mediate adhesion between matrix components and cells. Plasma fibronectin (CLG) mediates the attachment of monocytes (fibroblasts, macrophages) to various cell matrices and materials such as gelatin. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human FN1 |
| Other Notes: | Synthetic peptide located within the following region: NCRRPGGEPSPEGTTGQSYNQYSQR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |