Anti-PKLR antibody produced in rabbit
SIGMA/AV41699 - IgG fraction of antiserum
Synonym: Anti-PK1; Anti-PKL; Anti-Pyruvate kinase, liver and RBC; Anti-RPK
Product Type: Chemical
Immunohistochemistry Anti-PKLR: Cat. No. AV41699: Immunohistochemistry of PKLR in Human Kidney tissue with PKLR antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV41699). Lanes 1. Antibody dilution (concentration) 5.0 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 58 kDa |
| NCBI accession no. | NP_000289   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, pig, rabbit, bovine, dog, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P30613-2 |
| Application: | Anti-PKLR antibody produced in rabbit has been used in western blotting. |
| Biochem/physiol Actions: | Pyruvate kinase (PKLR) is needed for energy generation in erythrocytes. Deficiency of PKLR in mice reduces the risk of blood-stage malarial parasite Plasmodium chabaudi induced infection. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Pyruvate kinase (PKLR) is a liver/erythrocyte-specifi |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human PKLR |
| Other Notes: | Synthetic peptide located within the following region: STSIIATIGPASRSVERLKEMIKAG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |