Anti-COBLL1 antibody produced in rabbit
SIGMA/AV42423 - affinity isolated antibody
Synonym: Anti-COBL-like 1; Anti-KIAA0977
Product Type: Chemical
Immunohistochemistry Anti-COBLL1: Cat. No. AV42423: Immunohistochemistry of COBLL1 in Human Kidney tissue with COBLL1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV42423). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 128 kDa |
| NCBI accession no. | NP_055715   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, dog, rat, mouse, rabbit, human, guinea pig, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q53SF7 |
| Application: | Anti-COBLL1 polyclonal antibody is used to tag COBL-like 1 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a prognostic indicator for malignant pleural mesothelioma. |
| Biochem/physiol Actions: | Anti-COBLL1 polyclonal antibody reacts with human, mouse, rat, and canine COBL-like 1 proteins. |
| Biochem/physiol Actions: | The function remains known. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | COBLL1, a negative regulator of apoptosis in cultured tumor cells, has been identified as a component of a robust predictive four gene ratio test for survival of patients with malignant pleural mesothelioma. The previously assigned protein identifier A6NMZ3 has been merged into Q53SF7. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human COBLL1 |
| Other Notes: | Synthetic peptide located within the following region: SAPATPLVNKHRPTFTRSNTISKPY |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |