Anti-ANKRD2 antibody produced in rabbit
SIGMA/AV42559 - affinity isolated antibody
Synonym: Anti-ARPP; Anti-Ankyrin repeat domain 2 (stretch responsive muscle); Anti-MGC104314
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV42559). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 49 kDa |
| NCBI accession no. | NP_001123453   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | guinea pig, horse, mouse, rabbit, human, dog, bovine, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q3B778 |
| Application: | Anti-ANKRD2 polyclonal antibody is used to tag Ankyrin repeat domain 2 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role Ankrd2 in muscle cell development. |
| Biochem/physiol Actions: | ANKRD2 may play an important role in skeletal muscle hypertrophy. |
| Biochem/physiol Actions: | Anti-ANKRD2 antibody reacts with canine, human, mouse, and rat ankyrin repeat domain 2 (stretch responsive muscle) proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), a MARP mechanosensing protein, is believed to be involved in skeletal muscle hypertrophy through the regulation of cell signaling and gene expression within muscle cells. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human ANKRD2 |
| Other Notes: | Synthetic peptide located within the following region: QEEENEKLRGDARQKLPMDLLVLED |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |