Anti-CHAC1 antibody produced in rabbit
SIGMA/AV42623 - affinity isolated antibody
Synonym: Anti-ChaC, cation transport regulator homolog 1 (E. coli); Anti-MGC4504
Product Type: Chemical
Western Blotting JOURNAL CITATION: Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1. By: Joo, N. E., Ritchie, K., et al. in Cancer Med, 2012. PubMed ID: 23342279 Image collected and cropped by CiteAb from the following publication, (http://doi.wiley.com/10.1002/cam4.35), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Western Blotting JOURNAL CITATION: Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1. By: Joo, N. E., Ritchie, K., et al. in Cancer Med, 2012. PubMed ID: 23342279 Image collected and cropped by CiteAb from the following publication, (http://doi.wiley.com/10.1002/cam4.35), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Western Blotting JOURNAL CITATION: Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1. By: Joo, N. E., Ritchie, K., et al. in Cancer Med, 2012. PubMed ID: 23342279 Image collected and cropped by CiteAb from the following publication, (http://doi.wiley.com/10.1002/cam4.35), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Immunoblotting Cell Type: 721_B (Cat. No. AV42623). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B
Western Blotting Western Blot of CHAC1 in Human RPMI 8226 Whole Cell with CHAC1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 24 kDa |
| NCBI accession no. | NP_077016   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | pig, rabbit, human, rat, mouse, dog, bovine, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9BUX1 |
| Application: | Anti-CHAC1 polyclonal antibody is used to tag cation transport regulator-like protein 1 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of CHAC1 in the regulation of apoptosis via the unfolded protein response pathway. |
| Biochem/physiol Actions: | Anti-CHAC1 polyclonal antibody reacts with human, canine, bovine, rat, mouse, mouse, rat, and human cation transport regulator-like protein 1 proteins. |
| Biochem/physiol Actions: | CHAC1 belongs to the chaC family. The exact function of CHAC1 remains unknown. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | CHAC1/MGC4504 (cation transport regulator-like protein 1), a novel gene regulated by the atherosclerotic lesion component ox-PAPC (oxidized 1-palmitoyl-2-arachidonyl |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human CHAC1 |
| Other Notes: | Synthetic peptide located within the following region: TPQNPGYLGPAPEEAIATQILACRG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |