Anti-EGFL8 antibody produced in rabbit
SIGMA/AV42656 - IgG fraction of antiserum
Synonym: Anti-C6orf8; Anti-DAQB-143M3.8; Anti-
Product Type: Chemical
Immunohistochemistry Anti-EGFL8: Cat. No. AV42656: Immunohistochemistry of EGFL8 in Human Muscle tissue with EGFL8 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV42656). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
Immunoblotting EGFL8: Cat. No. AV42656: Western blot analysis of EGFL8 in Human HepG2 cell lysates with EGFL8 antibody at 1.0 μg/mL.
Immunoblotting EGFL8: Cat. No. AV42656: Western blot analysis of EGFL8 in Human HeLa cell lysates with EGFL8 antibody at 1.0 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 32 kDa |
| NCBI accession no. | NP_085155   |
| shipped in | wet ice |
| species reactivity | human, mouse, rat, pig, horse, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q99944 |
| Application: | Anti-EGFL8 polyclonal antibody is used to tag EGF-like-domain, multiple 8 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of EGF-like-domain, multiple 8 protein as a potential prognostic marker for gastrointestinal cancers such as gastric cancer and colorectal cancer. |
| Biochem/physiol Actions: | Anti-EGFL8 polyclonal antibody reacts with pig, bovine, human, mouse, and rat EGF-like-domain, multiple 8 proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | EGF-like-domain, multiple 8 (EGFL8), an EGFL7 paralog, is downregulated in metastatic colorectal cancers (CRC) making it a potential prognostic marker for poor prognosis in CRC and advanced gastric cancer. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human EGFL8 |
| Other Notes: | Synthetic peptide located within the following region: QAGAWVRAVLPVPPEELQPEQVAEL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |