Anti-FKBP6 antibody produced in rabbit
SIGMA/AV43027 - IgG fraction of antiserum
Synonym: Anti-FK506 binding protein 6, 36 kDa; Anti-FKBP36; Anti-MGC87179; Anti-PPIase
Product Type: Chemical
Immunohistochemistry Anti-FKBP6: Cat. No. AV43027: Immunohistochemistry of FKBP6 in Human Kidney tissue with FKBP6 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV43027). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 53 kDa |
| NCBI accession no. | NP_003593   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, rabbit, pig, bovine, human, dog, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O75344 |
| Biochem/physiol Actions: | FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human FKBP6 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: FCALSAEQQDQFPLQKVLKVAATER |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |