Anti-SYVN1 (AB2) antibody produced in rabbit
SIGMA/AV43360 - IgG fraction of antiserum
Synonym: Anti-HRD1; Anti-KIAA1810; Anti-MGC40372; Anti-Synovial apoptosis inhibitor 1, synoviolin
Product Type: Chemical
Immunoblotting Cell Type: transfected 293T (Cat. No. AV43360). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type transfected 293T
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 67 kDa |
| NCBI accession no. | NP_115807   |
| shipped in | wet ice |
| species reactivity | dog, rat, bovine, mouse, rabbit, human, horse, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q86TM6 |
| Biochem/physiol Actions: | SYVN1 is a protein involved in endoplasmic reticulum (ER)-associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3′ UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SYVN1 |
| Other Notes: | Synthetic peptide located within the following region: QGLLPPFPPGMFPLWPPMGPFPPVP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |