Anti-PEMT antibody produced in rabbit
SIGMA/AV43558 - affinity isolated antibody
Synonym: Anti-MGC2483; Anti-PEAMT; Anti-PEMPT; Anti-PEMT2; Anti-PNMT; Anti-
Product Type: Chemical
Immunoblotting Cell Type: 721_B (Cat. No. AV43558). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B
Western Blotting Western Blot of PEMT in Rat liver with PEMT antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 26 kDa |
| NCBI accession no. | NP_009100   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, rabbit, human, horse, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9UBM1 |
| Biochem/physiol Actions: | PEMT is an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene encodes PEMT protein is within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The previously assigned protein identifier Q9BW86 has been merged into Q9UBM1. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human PEMT |
| Other Notes: | Synthetic peptide located within the following region: GWAIMHASPTGLLLTVLVALTYIVA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |