Anti-SLC1A4 antibody produced in rabbit
SIGMA/AV43827 - affinity isolated antibody
Synonym: Anti-ASCT1; Anti-SATT; Anti-Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Product Type: Chemical
Immunohistochemistry SLC1A4 Antibody: Cat. No. AV43827: Immunohistochemistry analysis of SLC1A4 in Human Pineal Tissue with SLC1A4 Antibody 5.0 μg/mL. Observed Staining: Cytoplasm and membrane in Human Pineal Tissue
Immunoblotting Cell Type: transfected 293T (Cat. No. AV43827). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type transfected 293T
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 56 kDa |
| NCBI accession no. | NP_001129053   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, guinea pig, dog, rat, mouse, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P43007 |
| Application: | Anti-SLC1A4 polyclonal antibody is used to tag solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 in the concentrative uptake of neutral amino acids such as alanine, glutamate, serine, cysteine and the imino acids, hydroxyproline and proline. |
| Biochem/physiol Actions: | Anti-SLC1A4 polyclonal antibody reacts with bovine, human, mouse, rat, chicken, and zebrafish solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 proteins. |
| Biochem/physiol Actions: | SLC1A4 is a transporter for alanine, serine, cysteine, and threonine. It exhibits sodium dependence. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 (ASCT1, SATT, SLC1A4) is a sodium dependent concentrative transporter of neutral amino acids such as alanine, glutamate, serine, cysteine and the imino acids, hydroxyproline and proline. Defective SLC1A4 has been linked to multiple system atrophy (MSA), an adult-onset sporadic neurodegenerative disease. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human SLC1A4 |
| Other Notes: | Synthetic peptide located within the following region: ATKKGEQELAEVKVEAIPNCKSEEE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |