Anti-SLC7A1 antibody produced in rabbit
SIGMA/AV43838 - affinity isolated antibody
Synonym: Anti-ATRC1; Anti-CAT-1; Anti-ERR; Anti-HCAT1; Anti-REC1L; Anti-Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Product Type: Chemical
Immunoblotting
Cell Type: B cell lysate (Cat. No. AV43838).
Lanes
1. Antibody dilution (concentration) 1.0 μg/mL in 5% skim milk/PBS buffer
Cell Type: B cell lysate (Cat. No. AV43838).
Lanes
1. Antibody dilution (concentration) 1.0 μg/mL in 5% skim milk/PBS buffer
Immunoblotting SLC7A1 Antibody: Cat. No. AV43838: Western Blot analysis of SLC7A1 in Human Jurkat cell lysates with SLC7A1 Antibody at 1.0 μg/mL.
Western Blotting Western Blot of SLC7A1 in Human 721_B with SLC7A1 antibody at 1 μg/mL
Western Blotting Western Blot of SLC7A1 in Human MDA-MB-435s with SLC7A1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 68 kDa |
| NCBI accession no. | NP_003036   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rabbit, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P30825 |
| Application: | Anti-SLC7A1 polyclonal antibody is used to tag Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 in cationic amino acid uptake and retrovirus infection mechanisms and pathogenesis. |
| Biochem/physiol Actions: | Anti-SLC7A1 polyclonal antibody reacts with human and pig solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 proteins. |
| Biochem/physiol Actions: | SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1/ high affinity cationic amino acid transporter 1 (SLC7A1, ATRC1, CAT-1, ERR, REC1L) is a y+ system cationic amino acid transporter family member that supports arginine uptake and nitric oxide (NO) production. Mouse CAT-1 is a viral receptor for ecotropic murine leukemia virus (MLV) (eMLV), making it a model for study of retrovirus infection mechanisms and pathogenesis. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SLC7A1 |
| Other Notes: | Synthetic peptide located within the following region: LGFIMVSGFVKGSVKNWQLTEEDFG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |