Anti-SLC25A22 antibody produced in rabbit
SIGMA/AV44041 - IgG fraction of antiserum
Synonym: Anti-FLJ13044; Anti-GC1; Anti-Solute carrier family 25 (mitochondrial carrier: glutamate), member 22
Product Type: Chemical
Immunohistochemistry Anti-SLC25A22: Cat. No. AV44041: Immunohistochemistry of SLC25A22 in Human Muscle tissue with SLC25A22 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV44041). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| NCBI accession no. | NP_078974   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9H936 |
| Application: | Anti-SLC25A22 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml. |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunoprecipitation (1 paper) |
| Biochem/physiol Actions: | SLC25A22 (GC1) is a mitochondrial glutamate carrier that transport glutamine across the inner mitochondrial membrane. The transport of glutamate to the cytoplasm from mitochondria by SLC25A22 regulates the secretion of insulin secretory vesicles in the islet β-cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SLC25A22 |
| Other Notes: | Synthetic peptide located within the following region: LQDAGRIAAQRKILAAQGQLSAQGG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |