Anti-TGFBI antibody produced in rabbit
SIGMA/AV44268 - IgG fraction of antiserum
Synonym: Anti-BIGH3; Anti-CDB1; Anti-CDG2; Anti-CDGG1; Anti-CSD; Anti-CSD1; Anti-CSD2; Anti-Transforming growth factor, β-induced, 68 kDa
Product Type: Chemical
Immunofluorescence Immunofluorescence of TGFBI in Human cornea with TGFBI antibody at 4-8 μg/mL
Immunoblotting Cell Type: Jurkat (Cat. No. AV44268). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
Western Blotting Western Blot of TGFBI in Jurkat with TGFBI antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 46 kDa |
| NCBI accession no. | NP_000349   |
| shipped in | wet ice |
| species reactivity | horse, human, guinea pig, mouse, bovine, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: suitable | |
| UniProt accession no. | Q15582 |
| Application: | Anti-TGFBI polyclonal antibody is used to tag transforming growth factor, β 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of transforming growth factor, β 1 in cell signaling within a wide range of cell types. |
| Biochem/physiol Actions: | Anti-TGFBI polyclonal antibody reacts with chicken, human, mouse, rat, bovine, pig, and rabbit transforming growth factor, β 1 proteins. |
| Biochem/physiol Actions: | TGFBI Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Transforming growth factor, β-induced, 68 kDa (TGFB1, BIGH3, CDB1, CDG2, CDGG1, CSD) is a cell signaling protein with a wide range of functions, mostly as a negative/suppressive modulator of cell growth. TGFB1 is a modulator of immune function and an inducer of cell transformation. The actions of TGFB1 are mediated via transforming growth factor β receptors. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human TGFBI |
| Other Notes: | Synthetic peptide located within the following region: LKNNVVSVNKEPVAEPDIMATNGVV |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |