Anti-PPIB (AB2) antibody produced in rabbit
SIGMA/AV44366 - IgG fraction of antiserum
Synonym: Anti-CYP-S1; Anti-CYPB; Anti-MGC14109; Anti-MGC2224; Anti-Peptidylprolyl isomerase B (cyclophilin B); Anti-SCYLP
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 24 kDa |
NCBI accession no. | NP_000933 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, horse, rabbit, mouse, dog, bovine, rat, guinea pig |
storage temp. | −20°C |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | A8K534 |
Application: | Anti-PPIB (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml. |
Biochem/physiol Actions: | Peptidylprolyl isomerase B (PPIB; cyclophilin B) is a protein released with secretory pathway in the biological fluids by the rough endoplasmic reticulum. It is involved in the regulation of cyclosporine A-mediated immunosuppression. Mutations in the PPIB gene cause a delay in procollagen chain association in osteoblasts that is one of the features of osteogenesis imperfecta phenotypes. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human PPIB |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: VVFGKVLEGMEVVRKVESTKTDSRD |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |