Anti-MTUS1 antibody produced in rabbit
SIGMA/AV44418 - IgG fraction of antiserum
Synonym: Anti-ATIP; Anti-DKFZp586D1519; Anti-DKFZp686F20243; Anti-FLJ14295; Anti-KIAA1288; Anti-MP44; Anti-MTSG1; Anti-Mitochondrial tumor suppressor 1
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 48 kDa |
NCBI accession no. | NP_065800 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | rabbit, rat, guinea pig, dog, mouse, human, horse |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | western blot: suitable |
UniProt accession no. | Q9ULD2-3 |
Application: | Anti-MTUS1 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml. |
Biochem/physiol Actions: | MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human MTUS1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: QLLACGNTKFEALTVVIQHLLSERE |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |