Anti-ACVR2B antibody produced in rabbit
SIGMA/AV45043 - affinity isolated antibody
Synonym: Acvr2B Antibody; Acvr2B Antibody - Anti-ACVR2B antibody produced in rabbit; Anti-Activin A receptor, type IIB
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV45043). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 33 kDa |
| NCBI accession no. | NP_001097   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, human, horse, sheep, bovine, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q13705 |
| Application: | Anti-ACVR2B antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml. |
| Biochem/physiol Actions: | Activin A receptor, type IIB (ACVR2B) binds activin ligands that promote growth and differentiation via the TGF-β signaling. ACVR2B is expressed in adult hypothalamus and forebrain. Activin receptors IIA and IIB may regulate germ cell proliferation in the human ovary during primordial follicle formation and in mouse testis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human ACVR2B |
| Other Notes: | Synthetic peptide located within the following region: HDAEARLSAGCVEERVSLIRRSVNG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |