Anti-CDH8 antibody produced in rabbit
SIGMA/AV45176 - affinity isolated antibody
Synonym: Anti-Cadherin 8, type 2; Anti-Nbla04261
Product Type: Chemical
Immunohistochemistry Anti-CDH8: Cat. No. AV45176: Immunohistochemistry of CDH8 in Human Kidney tissue with CDH8 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV45176). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 81 kDa |
| NCBI accession no. | NP_001787   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, dog, bovine, rat, horse, rabbit, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P55286 |
| Application: | Anti-CDH8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml. |
| Biochem/physiol Actions: | CDH8 (Cadherin 8, type II), a classical cadherin, is a membrane protein that mediates calcium-dependent cell-cell adhesion. It is expressed predominantly in brain and modulates synaptic adhesion and axon growth. Microdeletions in CDH8 gene result in increased susceptibility to autism and learning disability. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human CDH8 |
| Other Notes: | Synthetic peptide located within the following region: HENAALNSVIGQVTARDPDITSSPI |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |