Anti-PTPN1 antibody produced in rabbit
SIGMA/AV45360 - affinity isolated antibody
Synonym: Anti-PTP1B; Anti-Protein tyrosine phosphatase, non-receptor type 1
Product Type: Chemical
Immunoblotting Cell Type: transfected 293T (Cat. No. AV45360). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type transfected 293T
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 50 kDa |
| NCBI accession no. | NP_002818   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, mouse, dog, bovine, rat, guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P18031 |
| Application: | Anti-PTPN1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml. |
| Biochem/physiol Actions: | Protein tyrosine phosphatase, non-receptor type 1 (PTPN1) is the first member of protein tyrosine phosphatase (PTP) family to be identified. The members of this family are involved in cell growth, differentiation and mitosis. PTPN1 dephosphorylates insulin receptor, JAK2 and TYK2 kinases and negatively regulates cell signaling mediated by these proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human PTPN1 |
| Other Notes: | Synthetic peptide located within the following region: SGSLSPEHGPVVVHCSAGIGRSGTF |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |