Anti-SMPD2 antibody produced in rabbit
SIGMA/AV45417 - IgG fraction of antiserum
Synonym: Anti-NSMASE; Anti-Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV45417). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 48 kDa |
| NCBI accession no. | NP_003071   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | O60906 |
| Application: | Anti-SMPD2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml. |
| Biochem/physiol Actions: | Sphingomyelin phosphodiesterase 2, neutral membrane (SMPD2) is a sphingomyelin phosphodiesterase that hydrolyzes sphingomyelin to phosphocholine and ceramide. It is expressed mainly in neurons of central nervous system and is important in cell growth, differentiation, and apoptosis. SMPD2 is important in the regulation of late embryonic and postnatal development. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SMPD2 |
| Other Notes: | Synthetic peptide located within the following region: RQKLSPTYPAAHHFRSGIIGSGLCV |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |