Anti-RARB antibody produced in rabbit
SIGMA/AV45601 - affinity isolated antibody
Synonym: Anti-HAP; Anti-NR1B2; Anti-RRB2; Anti-Retinoic acid receptor, β
Product Type: Chemical
Immunohistochemistry Anti-RARB: Cat. No. AV45601: Immunohistochemistry of RARB in Brain, cortex tissue with RARB antibody at 5.0 μg/mL.
Immunoblotting Cell Type: fetal brain (Cat. No. AV45601). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal brain
Western Blotting Western Blot of RARB in Mouse Skeletal Muscle with RARB antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 50 kDa |
| NCBI accession no. | NP_000956   |
| shipped in | wet ice |
| species reactivity | human, rabbit, horse, dog, bovine, pig, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P10826 |
| Biochem/physiol Actions: | RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human RARB |
| Other Notes: | Synthetic peptide located within the following region: SAKGAERVITLKMEIPGSMPPLIQE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |