Anti-RORA (AB3) antibody produced in rabbit
SIGMA/AV45608 - IgG fraction of antiserum
Synonym: Anti-MGC119326; Anti-MGC119329; Anti-NR1F1; Anti-RAR-related orphan receptor A; Anti-ROR1; Anti-ROR2; Anti-ROR3; Anti-RZRA
Product Type: Chemical
Immunohistochemistry Anti-RORA (ab3): Cat. No. AV45608: Immunohistochemistry of RORA in Human Kidney tissue with RORA antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV45608). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
Western Blotting Western Blot of RORA in Jurkat with RORA antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 63 kDa |
| NCBI accession no. | NP_599022   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | sheep, mouse, dog, horse, rat, guinea pig, bovine, human, goat, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P35398 |
| Application: | Anti-RORA (AB3) antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml. |
| Biochem/physiol Actions: | Retinoic acid related orphan receptor A (RORA), a member of the retinoid-related orphan family of nuclear receptors, is a ligand-dependent transcription factor. RORA is widely expressed and enhances p53-dependent apoptosis. RORA is important for the development of the cerebellum and it is required for the maturation of photoreceptors in the retina. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human RORA |
| Other Notes: | Synthetic peptide located within the following region: GHTPEGSKADSAVSSFYLDIQPSPD |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |