Anti-IFIT3 antibody produced in rabbit
SIGMA/AV46034 - affinity isolated antibody
Synonym: Anti-CIG-49; Anti-GARG-49; Anti-IFI60; Anti-IFIT4; Anti-IRG2; Anti-ISG60; Anti-
Product Type: Chemical
Immunohistochemistry Anti-IFIT3: Cat. No. AV46034: Immunohistochemistry of IFIT3 in Human Kidney tissue with IFIT3 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV46034). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2
Western Blotting Western Blot of IFIT3 in Human PANC1 Whole Cell with IFIT3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 56 kDa |
| NCBI accession no. | NP_001540   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O14879 |
| Application: | Anti-IFIT3 polyclonal antibody is used to tag interferon-induced protein with tetratricopeptide repeats 3 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and level of interferon-induced protein with tetratricopeptide repeats 3 in cells responding to interferon induction such as occurs during RNA virus infection. |
| Biochem/physiol Actions: | Anti-IFIT3 polyclonal antibody reacts with human, mouse, bovine, and rat interferon-induced protein with tetratricopeptide repeats 3 proteins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) is an interferon-stimulated gene induced by RNA virus infections, lipopolysaccharides and double-stranded RNA. IFIT3 and its family members (IFIT1, IFIT2, IFIT5) are involved in protein:protein interactions the a effect processes such as translation initiation, virus replication, cell migration, proliferation and ds-RNA signaling. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human IFIT3 |
| Other Notes: | Synthetic peptide located within the following region: ATMYNLLAYIKHLDGNNEAALECLR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |