Anti-ANP32E antibody produced in rabbit
SIGMA/AV46349 - affinity isolated antibody
Synonym: Anti-Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member E; Anti-LANP-L; Anti-LANPL; Anti-MGC5350
Product Type: Chemical
Immunohistochemistry Anti-ANP32E: Cat. No. AV46349: Immunohistochemistry of ANP32E in Human Kidney tissue with ANP32E antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV46349). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2
Western Blotting Western Blot of ANP32E in Human 293T Whole Cell with ANP32E antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| NCBI accession no. | NP_001129950   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, horse, rabbit, human, dog, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9BTT0 |
| Application: | Anti-ANP32E antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml. It is also useful for immunohistochemistry at a concentration of 4-8μg/ml. |
| Biochem/physiol Actions: | ANP32E [Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member E] also referred to as LANP-L, LANPL or MGC5350 is a histone chaperone located on chromosome 1q22 and is primarily expressed in human peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It facilitates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome. It also blocks the activity of protein phosphatase 2A (PP2A) but not the protein phosphatase 1. Additionally, it may play a pivotal role in cerebellar development and synaptogenesis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ANP32E |
| Other Notes: | Synthetic peptide located within the following region: EDNEAPDSEEEDDEDGDEDDEEEEE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |