Anti-LMNB2 antibody produced in rabbit
SIGMA/AV46356 - affinity isolated antibody
Synonym: Anti-LAMB2; Anti-LMN2; Anti-Lamin B2; Anti-MGC2721
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV46356). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 68 kDa |
| NCBI accession no. | NP_116126   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, horse, guinea pig, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q03252 |
| Application: | Anti-LMNB2 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml. |
| Biochem/physiol Actions: | LMNB2 (lamin B2) gene also referred to as LAMB2, LMN2, or MGC2721 encodes for a B type nuclear lamin. Lamins consist of two types, A and B, and are involved in nuclear stability chromatin structure and gene expression. Lamin B which is a structural component of the interphase nuclear lamina facilitates the stimulation of microtubule assembly and organization in mitosis. Mutation in LMNB2 gene leads to acquired partial lipodystrophy. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human LMNB2 |
| Other Notes: | Synthetic peptide located within the following region: MATPLPGRAGGPATPLSPTRLSRLQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |