Anti-LMAN2 (AB1) antibody produced in rabbit
SIGMA/AV46788 - affinity isolated antibody
Synonym: Anti-C5orf8; Anti-GP36B; Anti-Lectin, mannose-binding 2; Anti-VIP36
Product Type: Chemical
Immunohistochemistry Anti-LMAN2 (ab1): Cat. No. AV46788: Immunohistochemistry of LMAN2 in Human Kidney tissue with LMAN2 antibody at 4-8 μg/mL.
Immunohistochemistry LMAN2 Antibody: Cat. No. AV46788: Immunohistochemistry analysis of LMAN2 in Human Lung Tissue with LMAN2 Antibody 5.0 μg/mL. Observed Staining: Cytoplasm of pneumocytes
Immunoblotting Cell Type: Jurkat (Cat. No. AV46788). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| NCBI accession no. | NP_006807   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, bovine, rabbit, rat, mouse, dog, horse, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q12907 |
| Application: | Anti-LMAN2 (AB1) polyclonal antibody is used to tag lectin, mannose-binding 2 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of lectin, mannose-binding 2 in the secretion of high mannose glycoproteins. |
| Biochem/physiol Actions: | Anti-LMAN2 (AB1) polyclonal antibody reacts with zebrafish, bovine, human, rat, canine, and mouse lectin, mannose-binding 2 proteins. |
| Biochem/physiol Actions: | LMAN2 plays a role as an intracellular lectin in the early secretory pathway. It interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. It is involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Lectin, mannose-binding 2 (LMAN2, VIP36) is an intracellular, integral membrane protein that functions as a lectin of the post-Golgi secretory pathway. LMAN2 facilitates the secretion of high mannose glycoproteins predominantly via the apical surface of cells. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human LMAN2 |
| Other Notes: | Synthetic peptide located within the following region: SLIKPYQGVGSSSMPLWDFQGSTML |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |