Anti-LETM1 antibody produced in rabbit
SIGMA/AV46881 - IgG fraction of antiserum
Synonym: Anti-Leucine zipper-EF-hand containing transmembrane protein 1
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV46881). Lanes 1. Antibody dilution (concentration) 5.0 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 60 kDa |
| NCBI accession no. | NP_036450   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, mouse, horse, guinea pig, bovine, human, rat |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | O95202 |
| Application: | Anti-LETM1 antibody produced in rabbit is suitable for western blotting at a concentration of 5μg/mL. |
| Biochem/physiol Actions: | LETM1 (leucine zipper-EF-hand containing transmembrane protein 1) gene encodes a single-pass membrane protein localized in the inner mitochondrial membrane. It plays a pivotal role in maintaining the mitochondrial tubular shape as well as cristae organization. It also facilitates the normal mitochondrial morphology and cellular viability. Mutation in LETM1 gene leads to Wolf-Hirschhorn syndrome. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human LETM1 |
| Other Notes: | Synthetic peptide located within the following region: MALKNKAAKGSATKDFSVFFQKIRE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |