Anti-SV2A antibody produced in rabbit
SIGMA/AV47093 - affinity isolated antibody
Synonym: Anti-KIAA0736; Anti-SV2; Anti-Synaptic vesicle glycoprotein 2A
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of SV2A in Human Brain, Cortex with SV2A antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of SV2A in Human Kidney with SV2A antibody at 4-8 μg/mL
Immunoblotting Cell Type: fetal brain (Cat. No. AV47093). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal brain
Western Blotting Western Blot of SV2A in Mouse Pancreas with SV2A antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| mol wt | 83 kDa |
| NCBI accession no. | NP_055664   |
| packaging | pkg of 100 μL buffered aqueous solution |
| pkg of 50 μg lyophilized powder | |
| Quality Level | 100 |
| species reactivity | human, guinea pig, mouse, bovine, horse, dog, rabbit, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q7L0J3 |
| Application: | Anti-SV2A antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/mL. |
| Biochem/physiol Actions: | SV2A (synaptic vesicle glycoprotein 2A) gene is a multi-pass membrane protein that belongs to major facilitator superfamily. It regulates the cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation and facilitates the synaptic transmission. SV2A serves as a binding site for the antiepileptic drug levetiracetam and may decrease the neuronal excitability. Mutation in SV2A gene results in schizophrenia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SV2A |
| Sequence: | Synthetic peptide located within the following region: LENQIHRGGQYFNDKFIGLRLKSVS |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |