Anti-PA2G4 (AB1) antibody produced in rabbit
SIGMA/AV47601 - affinity isolated antibody
Synonym: Anti-EBP1; Anti-HG4-1; Anti-
Product Type: Chemical
Immunohistochemistry Anti-PA2G4 (ab1): Cat. No. AV47601: Immunohistochemistry of PA2G4 in Lung, respiRatory epithelium tissue with PA2G4 antibody at 4-8 μg/mL.
Immunohistochemistry PA2G4 Antibody: Cat. No. AV47601: Immunohistochemistry analysis of PA2G4 in Human Bronchial Epithelial Tissue with PA2G4 Antibody 5.0 μg/mL. Observed Staining: Cytoplasmic
Immunoblotting Cell Type: HepG2 (Cat. No. AV47601). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type HepG2
Immunoblotting PA2G4: Cat. No. AV47601: Western blot analysis of PA2G4 in Human Fetal Brain cell lysates with PA2G4 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 44 kDa |
| NCBI accession no. | NP_006182   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, guinea pig, bovine, rabbit, human, dog, horse, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9UQ80 |
| Application: | Rabbit Anti-PA2G4 antibody is suitable for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions: | PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | PA2G4 codes for an RNA-binding protein that modulates growth. It is homologous to the mouse cell cycle protein p38-2G4. PA2G4 may be involved in eukaryotic DNA replication and ErbB-3-mediated signaling pathways. Rabbit Anti-PA2G4 antibody recognizes human, mouse, rat, canine, bovine, and zebrafish PA2G4. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human PA2G4 |
| Other Notes: | Synthetic peptide located within the following region: LLQPFNVLYEKEGEFVAQFKFTVLL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |