Anti-SETD2 antibody produced in rabbit
SIGMA/AV47617 - IgG fraction of antiserum
Synonym: Anti-FLJ16420; Anti-FLJ22472; Anti-FLJ23184; Anti-FLJ45883; Anti-HIF-1; Anti-HSPC069; Anti-HYPB; Anti-SET domain containing 2
Product Type: Chemical
Immunofluorescence Tissue: placenta (Cat. No. AV47617). Specification 1. Antibody dilution (concentration) 4-8 μg/mL
Immunoblotting Cell Type: HepG2 (Cat. No. AV47617). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| form | buffered aqueous solution |
| mol wt | 97 kDa |
| NCBI accession no. | NP_054878   |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9BYW2 |
| Biochem/physiol Actions: | Huntington′s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SETD2 |
| Other Notes: | Synthetic peptide located within the following region: SDEDSVRTSSSQRSHDLKFSASIEK |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |