Anti-NPNT antibody produced in rabbit
SIGMA/AV47815 - affinity isolated antibody
Synonym: Anti-EGFL6L; Anti-NephroNectin; Anti-POEM
Product Type: Chemical
Immunoblotting Cell Type: HepG2 (Cat. No. AV47815). Lanes 1. Antibody dilution (concentration) 1.0 μg/mL in cell type HepG2
Western Blotting Western Blot of NPNT in Human HepG2 with NPNT antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 62 kDa |
| NCBI accession no. | NP_001028219   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, guinea pig, human, rabbit, mouse, horse, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q6UXI9 |
| Application: | Rabbit Anti-NPNT antibody is suitable for western blot applications at a concentration of 1μg/ml |
| Biochem/physiol Actions: | NPNT is a functional ligand of integrin alpha-8/beta-1 in kidney development. It regulates with integrin alpha-8/beta-1 the expression of GDNF which is essential for kidney development. It may also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | NPNT codes for a nephronectin that is an extracellular matrix protein associated with integrin alpha 8 beta1 in embryonic renal cells. Nephronectin expression has been implicated in diabetic nephropathy and glomerulosclerosis. Rabbit Anti-NPNT antibody recognizes rabbit, human, mouse, rat, chicken, bovine, and canine NPNT. |
| Immunogen: | Synthetic peptide directed towards the middle region of human NPNT |
| Other Notes: | Synthetic peptide located within the following region: TTGLTTIAPAASTPPGGITVDNRVQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |