Anti-STRAP (AB1) antibody produced in rabbit
SIGMA/AV48038 - affinity isolated antibody
Synonym: Anti-MAWD; Anti-PT-WD; Anti-
Product Type: Chemical
Immunohistochemistry Anti-STRAP (AB1): Cat. No. AV48038: Immunohistochemistry of STRAP in Human Skin tissue with STRAP antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV48038). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 38 kDa |
| NCBI accession no. | NP_009109   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, guinea pig, horse, rat, dog, human, mouse, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9Y3F4 |
| Application: | Rabbit Anti-STRAP antibody is suitable for IHC applications at a dilution of 1:150 and for western blot applications at a concentration of 0.5μg/ml. |
| Biochem/physiol Actions: | The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Serine/threonine kinase receptor associated protein (STRAP) is a poly(A) RNA binding protein that modulates type I collagen mRNA translation. It decreases the ubiquitination of Notch3 and negatively regulates ASK1. Rabbit Anti-STRAP antibody recognizes human, mouse, rat, canine, bovine, and zebrafish STRAP. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human STRAP |
| Other Notes: | Synthetic peptide located within the following region: HIVKTVDFTQDSNYLLTGGQDKLLR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |