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Anti-ALDOA antibody produced in rabbit

SIGMA/AV48130 - IgG fraction of antiserum

Synonym: Anti-ALDA; Anti-Aldolase A, fructose-bisphosphate; Anti-MGC10942; Anti-MGC17716; Anti-MGC17767

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-AV48130-100UL 100 µL
$0.00
1/EA
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Immunoblotting Cell Type: HepG2 (Cat. No. AV48130). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2

 

antibody form IgG fraction of antiserum
antibody product type primary antibodies
biological source rabbit
clone polyclonal
concentration 0.5 mg - 1 mg/mL
conjugate unconjugated
form buffered aqueous solution
mol wt 39 kDa
NCBI accession no. NP_001121089 
shipped in wet ice
species reactivity dog, human, rabbit
storage temp. −20°C
target post-translational modification unmodified
technique(s) western blot: suitable
UniProt accession no. P04075 
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper) 
Application: Rabbit Anti-ALDOA antibody has been used for western blot applications at a dilution of 1:1000.
Biochem/physiol Actions: In glycolysis, ALDOA (Aldolase A, fructose-bisphosphate) catalyzes the reversible reaction of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate. High expression level of ALDOA is reported in various forms of malignant cancers, including human lung squamous, renal cell and hepatocellular carcinomas. ALDOA deficiency causes myopathy and hemolytic anemia.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: Aldolase A, fructose-bisphosphate (ALDOA) is a ubiquitous glycolytic enzyme expressed in developing embryo and in adult muscle. It is involved in a wide range of cellular functions such as maintenance of striated muscle contraction, cell shape and mobility, actin filament organization and ATP biosynthetic process.
Immunogen: Synthetic peptide directed towards the N terminal region of human ALDOA
Other Notes: Synthetic peptide located within the following region: MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTE
Physical form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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